Insulin clearance: an underappreciated modulator of plasma insulin concentration

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Insulin clearance: an underappreciated modulator of plasma insulin concentration.

Plasma glucose concentrations are tightly regulated and maintained within a narrow range in non-diabetic individuals. Maintenance of this physiological state is primarily a function of the ability of the pancreatic β-cells to modify insulin secretion rate (ISR), thus preventing wide-swings in plasma glucose concentrations. As a consequence, and in contrast to plasma glucose concentrations, plas...

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ژورنال

عنوان ژورنال: Journal of Investigative Medicine

سال: 2016

ISSN: 1081-5589,1708-8267

DOI: 10.1136/jim-2016-000149